Aizome’s sheet set is made out of virgin cotton, which means the sheets are “unbleached, chemical free, and organic,” Joshua Zeichner, MD, an associate professor of dermatology and Director of Cosmetic and Clinical Research in Dermatology at Mount Sinai Hospital in New York City, tells Real Simple. “They are ultra gentle on the skin,” Zeichner adds, “which is so important for people with conditions like eczema, where the skin barrier is disrupted.” These lightweight woven sheets are also antibacterial and hypoallergenic, and the brand says the ultra-soft material is soothing against irritated skin and breathable for extra comfort. Zeichner said that “it has been well documented that there are frictional forces between your skin and the sheets you sleep on,” which can impact the skin itself, especially when you’re already facing issues. " Soft, non-irritating fabrics are best for people with eczema," he said. To buy: From $239; aizomebedding.com. The Aizome sheets come in five sizes and colors to fit any mattress and blend in with most bedroom decor aesthetics. They’re packed with a flat and fitted sheet and two pillow cases. They also have an optional drawstring style bottom sheet for a near-guaranteed perfect fit that won’t pop off your mattress. Shoppers say the sheets are cooling to the touch, and one wrote, “If you like percale, you will love the feel of Aizome Sheets.” That same shopper said they love the sheets so much, they’ve replaced every other set they own with these. Another added that the sheets are “definitely the most comfortable and best constructed bedding” they’ve ever purchased and said they’re now “a customer for life.” A third shopper with allergies said they ordered them to find some relief and said they’ll be “purchasing again” since there aren’t “enough products to support people with allergies.” Give your sensitive skin and allergies some relief by ordering the virgin cotton Aizome sheet set today.